Science2026-09-24
古老的入侵推动了野猪的扩张和家猪的表型多样化Ancient introgression drives wild boar expansion and phenotypic diversification of domestic pigs
Nature2026-09-23
人脑疾病的单核转录组全关联研究Single-nucleus transcriptome-wide association study of human brain disorders
Nature2026-09-23
参考基因组和化石修订了蝙蝠家族的系统发育和生物地理学Reference genomes and fossils revise bat family phylogeny and biogeography
Nature2026-09-23
mTORC1在结节性硬化症中驱动细胞自主星形胶质细胞反应性mTORC1 drives cell-autonomous astrocyte reactivity in tuberous sclerosis
Nature2026-09-23
人类前额叶皮层的寿命单细胞转录组图谱Lifespan single-cell transcriptomic atlas of the human prefrontal cortex
Nature2026-09-23
跨脑疾病转录组脆弱性的单细胞图谱Single-cell atlas of transcriptomic vulnerability across brain disorders
Nature2026-09-23
TA重复序列断裂的MMEJ修复维持了ecDNA和癌症适应性MMEJ repair of breaks at TA repeats maintains ecDNA and cancer fitness
Nature2026-09-23
“0”着丝粒的突变动力学The mutational dynamics of the Arabidopsis centromeres
Cell综述2026-09-17
避免人工智能在健康和医学方面的常见失败Avoiding common failures in AI for health and medicine
Science2026-09-17
古老的“0”揭示了东天山青铜和铁器时代的独特祖先Ancient DNA unveils distinctive ancestries in the Bronze and Iron Ages of East Tianshan
Science2026-09-17
ASD风险突变小鼠中基于转录组的分类Transcriptome-based classification in mice with ASD-risk mutations
Science2026-09-17
CRISPR-Cas起源处“0”引导的“1”识别的非连续代码A noncontiguous code for RNA-guided DNA recognition at the origin of CRISPR-Cas
Science2026-09-17
VIPR RNA引导的DNA通过非连续几何三角形形成识别VIPR RNA-guided DNA recognition by noncontiguous geometric triplex formation
Science2026-09-17
用于腹部CT诊断的专家级通才AIAn expert-level generalist AI for abdominal CT diagnosis
Science2026-09-17
生殖系EGFR T790M突变和肺癌风险Germline EGFR T790M mutation and lung cancer risk
Cell2026-09-17
scBaseCount ： AI代理策划、标准化、自动更新的单细胞数据存储库scBaseCount: An AI agent-curated, standardized, auto-updated single-cell data repository
Cell2026-09-17
Tahoe-100M ：以单细胞分辨率绘制药物诱导的分子表型Tahoe-100M: Mapping drug-induced molecular phenotypes at single-cell resolution
Cell2026-09-17
老龄化生物学中人工智能的开放基准和语言模型An open benchmark and language models for AI in aging biology
Cell综述2026-09-17
虚拟细胞的世界模型A world model of the virtual cell
Cell综述2026-09-17
世界生物医学模型World models for biomedicine
Science2026-09-17
虚拟生物技术：用于治疗发现和开发的多药剂人工智能框架The Virtual Biotech: A multi-agent AI framework for therapeutic discovery and development
Nature2026-09-16
将研究论文重新构想为交互式和可靠的人工智能代理Reimagining research papers as interactive and reliable AI agents
Nature2026-09-16
RSV F及其被抗体中和的突变约束Mutational constraints on RSV F and its neutralization by antibodies
Nature2026-09-16
用于X射线到体积配准的快速患者特定神经网络Rapid patient-specific neural networks for X-ray to volume registration
Nature2026-09-16
使用PRIME ASSEMBLY进行靶向基因组整合和重排Targeted genomic integration and rearrangement using prime assembly
Nature2026-09-14
编码和非遗传蛋白质变异体扩展人体功能蛋白质组Encoded and non-genetic protein variants expand human functional proteome
Science2026-09-10
小鼠Y染色体的完整端粒到端粒序列The complete telomere-to-telomere sequence of a mouse Y chromosome
Science2026-09-10
古基因组学和栖息地模型揭示了羊毛犀牛的温带欧亚起源Paleogenomics and habitat modeling reveal temperate Eurasian origins of woolly rhinoceroses
Cell2026-09-10
通过表征学习解锁跨细胞状态的线粒体表型的4D时空景观4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning
Nature2026-09-09
使用GPN-Star预测全基因组功能约束Predicting genome-wide functional constraints with GPN-Star
Nature2026-09-09
集成特征定义了前列腺癌的突变过程Integrated signatures define mutational processes in prostate cancer
Nature2026-09-09
基于操作扰动蛋白质组学的虚拟细胞模型An operational perturbation proteomics-based virtual cell model
Nature2026-09-02
发育中人类大脑皮层胶质细胞类型的 3D 表观基因组图谱3D epigenome of glial cell types in developing human cortex
Nature2026-09-02
用人工智能设计物理实验Designing physics experiments with artificial intelligence
Nature2026-09-02
人格遗传关联的稳健推断及其相关因素Robust inference and correlates from genetic associations with personality
Nature2026-09-02
可解释深度学习提升人类对自动驾驶汽车的心理模型Explainable deep learning improves human mental models of self-driving cars
Cell2026-09-01
史前跨欧亚交流时期甘肃磨沟等遗址的基因组学与社会实践Genomics and social practices at Mogou and other Gansu sites during prehistoric trans-Eurasian exchange
Cell2026-09-01
炎症与纤维化的调控逻辑（综述）The regulatory logic linking inflammation and fibrosis
Cell2026-09（月级）
纹状体的跨物种单细胞图谱定义了细胞类型和亚区疾病的脆弱性Cross-species single-cell atlas of the striatum defines cell-type and subregion disease vulnerabilities
Cell2026-09（月级）
热量限制调节小鼠全基因组体细胞突变Caloric restriction modulates genome-wide somatic mutation in mice
Cell2026-09（月级）
Metax可实现宏基因组的准确跨域分类分析Metax enables accurate cross-domain taxonomic profiling of metagenomes
Cell2026-09（月级）
线粒体ATP通过染色质可及性促进T细胞分化Mitochondrial ATP promotes T cell differentiation through chromatin accessibility
Cell2026-09（月级）
挪威针叶树生殖发育的云杉时空计划Norway spruce spatiotemporal programs of conifer reproductive development
Cell2026-09（月级）
栖息在海洋内部的原核浮游生物的单细胞分辨基因组图谱Single-cell-resolved genome atlas of prokaryoplankton inhabiting the ocean’s interior
Cell2026-09（月级）
3D驯化过程中的染色质重塑定义了作物改良的新目标3D chromatin remodeling during domestication defines novel targets for crop improvement
Cell2026-09（月级）
通过代理人工智能走向自主科学Toward autonomous science with agentic artificial intelligence
Cell2026-09（月级）
逆转录转座子的直接细胞间传递Direct cell-to-cell transmission of retrotransposons
Cell2026-09（月级）
最小细菌的单细胞视觉蛋白质组揭示了基因表达机制的结构协调Single-cell visual proteomics of a minimal bacterium reveals structural coordination of gene expression machineries
Cell2026-09（月级）
促进恶病质微环境在胰腺癌中的空间演变Spatial evolution of a cachexia-promoting microenvironment in pancreatic cancer